The publications are listed in reverse chronological order, grouped into peer-reviewed texts and other publications. As far as available, the digital object identifier (DOI) is provided after each entry and links to the abstract or fulltext of the publication (depending on the availability of the journal at your institution).
Peer-reviewed scientific journals and books
[38] Backhaus, T., Faust, M. Predictive environmental risk assessment of chemical mixtures: a conceptual framework, Environmental Science and Technology, in press, http://dx.doi.org/10.1021/es2034125
[37] Silva, E., Rajapakse, N., Scholze, M., Backhaus, T., Ermler, S., Kortenkamp A. Joint effects of heterogeneous estrogenic chemicals in the E-Screen – exploring the applicability of concentration addition. Toxicological Sciences, 122(2), 383-394, 2011, doi:10.1093/toxsci/kfr103
[36] Backhaus, T., Porsbring, T., Arrhenius, A., Brosche, S., Johansson, P., Blanck, H. Single substance and mixture toxicity of 5 pharmaceuticals and personal care products to marine periphyton communities, Env. Tox. Chem, 30(9), 2030-2040, 2011, doi:10.1002/etc.586
[35] Brosché, S., Fick, J., Larsson, J., Backhaus, T. Effluent from antibiotic production induce tolerance development in natural freshwater bacterial communities, submitted
[34] Backhaus, T., Brooks, B., Kapustka, L. Chemical Risk Assessment: Pressures, Perceptions and Expectations. Integrated Environmental Assessment and Management, 6(3), 323-324, 2010, doi:10.1002/ieam.95
[33] Brosché S, Backhaus T. Toxicity of five protein synthesis inhibiting antibiotics and their mixture to limnic bacterial communities. Aquatic Toxicology, 99(4), 457-465,2010, doi:10.1016/j.aquatox.2010.06.008
[32] Boedeker W, Backhaus T. The scientific assessment of combined effects of risk factors – lessons from experimental biosciences for epidemiology? Europ. J. Epidemiology. 25(8), 539-546, 2010 doi:s10654-010-9464-2
[31] Porsbring T, Backhaus T, Johansson P, Kuylenstierna M, Blanck H. Mixture toxicity from PSII inhibitors on microalgal community succession is predictable by Concentration Addition. Environmental Toxicology and Chemistry, doi:10.1002/etc.346
[30] Frische, T., Faust, M., Meyer W., Backhaus T.: Toxic Masking and Synergistic Modulation of the Estrogenic Activity of Chemical Mixtures in a Yeast Estrogen Screen (YES). Env. Science and Pollution Research, 16(5), 593-603, doi: 10.1007/s11356-009-0184-7
[29] Hassold, E. Backhaus, T. “Chronic toxicity of five structurally diverse demethylase inhibiting fungicides to the crustacean Daphnia magna – a comparative assessment” Envi-ronmental Toxicology and Chemistry, 28(6), 1218-1226, 2009, doi:10.1897/08-339.1
[28] Porsbring, T. Blanck, H. Tjellström, H. Backhaus, T. “The toxicity of the human pharmaceutical Clotrimazole to natural marine microalgal communities” Aquatic Toxicology, 91, 203-211, 2009, doi:10.1016/j.aquatox.2008.11.003
[27] Backhaus, T., Sumpter, J., Blanck, H.: On the ecotoxicology of pharmaceutical mixtures. In “Pharmaceuticals in the Environment” ed. by K. Kümmerer, 3rd edition, Springer publishers, ISBN 978-3-540-74663-8, 2008, amazon link
[26] Kortenkamp, A., Faust, M., Scholze, M, Backhaus T,: Low-Level Exposure to Multiple Chemicals – Reason for Human Health Concerns? Environ. Health Persp. 115, S-1, 106-114, 2007, direct link
[25] Porsbring, T. Arrhenius, Å, Backhaus T, Kuylenstierna M, Scholze M, Blanck H, The SWIFT periphyton test for high-capacity assessments of toxicant effects on microalgal community development, J. Exp. Marine Biology and Ecology, 349, 299-312, 2007, doi:10.1016/j.jembe.2007.05.020
[24] Drost, W., Matzke, M. Backhaus, T.: Heavy metal toxicity to Lemna minor: studies on the time-dependence of growth inhibition and the recovery after exposure. Chemosphere, 67(1) 36-42, 2007, doi:10.1016/j.chemosphere.2006.10.018
[23] Junghans M, Backhaus T, Faust M, Scholze M, Grimme LH.: Application and validation of approaches for the predictive hazard assessment of realistic pesticide mixtures, Aquatic Toxicology, 76, 93-110, 2005, doi:10.1016/j.aquatox.2005.10.001
[22] Arrhenius Å, Backhaus T, Blanck H, Grönvall F, Junghans M, Scholze M.: Effects of three antifouling agents to algal communities and algal reproduction: Mixture toxicity studies with TBT, Irgarol, and Sea-Nine, Archives of Environmental Contamination and Toxicolology, 49, 1-13, 2006, doi:10.1007/s00244-005-1057-9
[21] Brian J, Harris CA, Scholze M, Backhaus T, Booy P, Lamoree M, Pojana G, Jonkers N, Runnalls T, Bonfä A, Marcomini A, Sumpter JP. Accurate Prediction of the Response of Freshwater Fish to a mixture of estrogenic chemicals, Environmental Health Perspectives, 113, 721-728, 2005, direct link
[20] Backhaus T, Arrhenius Å, Blanck, H: The toxicity of a mixture of dissimilarly acting substances to natural algal communities: predictive power and limitations of Independ-ent Action and Concentration Addition, Environmental Science and Technology, 38(23), 6363-7670, 2004
[19] Arrhenius Å, Grönvall F, Scholze M, Backhaus T, Blanck H: Predictability of mixture toxicity of 12 similarly acting congeneric inhibitors of photosystem II in marine pe-riphyton and epipsammon communities, Aquatic Toxicology, 68, 351-367, 2004
[18] Backhaus T, Faust M, Scholze M, Gramatica P, Vighi M, Grimme LH: The joint algal toxicity of phenylurea herbicides is equally predictable by concentration addition and independent action, Environmental Toxicology and Chemistry, 23(2), 258–264, 2004
[17] Backhaus T, Altenburger, R, Arrhenius, A, Blanck, H, Faust M, Finizio A., Gramatica P, Grote, M, Junghans, M, Meyer W, Pavan M, Porsbring T, Scholze M, Todeschini R, Vighi M, Walter H, Grimme LH: The BEAM project: prediction and assessment of mixture toxicities in the aquatic environment, Continental Shelf Research 23: 1757-1769, 2003
[16] Faust M, Altenburger R, Backhaus T, Blanck H, Boedeker W, Gramatica P, Hamer V, Scholze M, Vighi M, Grimme LH: Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action, Aquatic Toxicology, 63 (1), 43-63, 2003
[15] Drost W, Backhaus T, Vassilakaki M, Grimme LH: Mixture Toxicity of s-triazines to Lemna minor under conditions of simultaneous and sequential exposure Fresenius Envi-ronmental Bulletin (FEB), 12(6), 601-607, 2003
[14] Vighi M, Altenburger R, Arrhenius Å, Backhaus T, Bödeker W, Blanck H, Consolaro F, Faust M, Finizio A, Froehner K, Gramatica P, Grimme LH, Grönvall F, Hamer V, Scholze M, Walter H: Water quality objectives for mixtures of toxic chemicals: problems and perspectives; Ecotoxicology and Environmental Safety, 54 (2): 139-150, 2003
[13] Junghans M, Backhaus T, Faust M, Scholze M, Grimme LH: Predictability of Combined Effects of 8 Chloroacetanilide Herbicides on Algal Reproduction. Pest Management Science, 59(19), 1101-1110. 2003
[12] Junghans M, Backhaus T, Faust M, Scholze M, Grimme LH: Toxicity of Sulfonylurea Herbicides to the green alga Scenedesmus vacuolatus: Predictability of Combination Ef-fects, Bulletin of Environmental Contamination and Toxicology, 71 (3) 585-593, 2003
[11] Faust M, Altenburger R, Backhaus T, Blanck H, Bödeker W, Gramatica P, Hamer V, Scholze M, Vighi M, Grimme LH: Predicting the joint algal toxicity of multi-component s-triazine mixtures at low-effect concentrations of individual toxicants, Aquatic Toxi-cology, 56 (1), 13-32, 2001
[10] Scholze M, Boedeker W, Faust M, Backhaus T, Altenburger R, Grimme LH: A general best-fit method for concentration-response curves and the estimation of low-effect con-centrations, Environmental Toxicology and Chemistry, 20(2), 448-457, 2001
[9] Backhaus T, Altenburger R, Boedeker W, Faust M, Scholze M, Grimme LH: Predict-ability of the toxicity of a mixture of dissimilarly acting chemicals to Vibrio fischeri, Environmental Toxicology and Chemistry, 19(9), 2348-2356, 2000
[8] Backhaus T, Scholze M, Grimme LH: The single substance and mixture toxicity of qui-nolones to the bioluminescent bacterium Vibrio fischeri, Aquatic Toxicology, 49(1-2), 49-61, 2000
[7] Faust M, Altenburger R, Backhaus T, Boedeker W, Scholze M, Grimme LH: Predictive assessment of the aquatic toxicity of multiple chemical mixtures, Journal of Environ-mental Quality, 29,1063-1068, 2000
[6] Grimme LH, Backhaus T, Bödeker W, Faust M, Scholze M, Altenburger R: Kombinati-onswirkungen von Umweltchemikalien – Konzepte für die Vorhersage und ihre experi-mentelle Prüfung, UWSF – Zeitschrift für Umweltchemie und Ökotoxikologie, 12(4), 226-235, 2000
[5] Altenburger R, Backhaus T, Boedeker W, Faust M, Scholze,M, Grimme,L H: Predict-ability of the toxicity of multiple chemical mixtures to Vibrio fischeri: Mixtures com-posed of similarly acting chemicals, Environmental Toxicology and Chemistry, 19(9),2341-2347, 2000
[4] Backhaus T, Grimme LH: Bestimmung der aquatischen Toxizität von Antibiotika mit dem chronischen Leuchtbakterientest (Vibrio fischeri), in: A. E. Lison, H. A. Diehl: Medizinische Forschung und Gesundheitswissenschaften in Bremen, Pabst Verlag, Ber-lin, ISBN: 3-934252-77-X, 2000
[3] Froehner K, Backhaus T, Grimme LH: Bioassays with Vibrio fischeri for the assessment of delayed toxicity, Chemosphere, 40, 821-828, 2000
[2] Backhaus T, Grimme LH: The toxicity of antibiotic agents to the luminescent bacterium Vibrio fischeri, Chemosphere 38(14), 3291-3301,1999
[1] Thies F, Backhaus T, Bossmann B, Grimme, LH: Xenobiotic biotransformation in uni-cellular green algae – Involvement of cytochrome P450 in the activation and selectivity of the pyridazinone pro-herbicide metflurazon Plant Physiology, 112 (1): 361-370 1996
Other Publications
[12] Backhaus T, Faust M Blanck H Hazard and Risk Assessment of Chemical Mixtures under REACH–State of the Art, Gaps and Options for Improvement, Report to the Swedish Chemicals Agency, 2010. Direct download here.
[11] Kortenkamp, A, Backhaus, T , Faust M.: State of the Art Review of Mixture Toxicity. Report to the Commission of the European Union (Directorate General for the Environmen), 2009. Commission Website, Direct Link to PDF. Follow up by media and news services: Göteborgs Posten, Miljöaktuelt, Forskning.se, Medical News, Chemicals Health Monitor
[10] Hasselöv, M., Backhaus, T., Molander, S.: REACH missar nano!, Miljöforskning 3/4, p. 20. see also the press release at the website of the Swedish Research Council (FORMAS)
[9] Jonker, M., Gerhardt, A., Backhaus, T., C.A.M. van Gestel: Test design, mixture characterization and data evaluation. In: “Chemical mixtures in the environment” ed. by C.A.M. van Gestel, SETAC Press, submitted / in preparation
[8] Scholze, M, Backhaus, T: Principles of the experimental design of mixture studies involving vertebrates, Public Report of the EU-Project ACE (Analysing combination ef-fects of mixtures of estrogenic chemicals in marine and freshwater organisms)
[7] Backhaus, T, Kortenkamp, A: Principles of Mixture Testing, with Special Emphasis on the Problem whether Estrogenic Mixture Effects Occur at Low-Effect Concentrations, Public Report of the EU-Project ACE
[6] Scholze, M, Backhaus, T, Kortenkamp, A: Optimised mixture study designs for use in in vivo studies with fish, Public Report of the EU-Project ACE
[5] Frische, T, Backhaus, T: Evaluations of the impact of non-estrogenic aquatic pollutants on the effects of individual estrogenic chemicals, including an assessment of the influ-ence of non-estrogenic chemicals on the predictability of mixture effects, Public Report of the EU-Project ACE
[4] Faust M, Backhaus, T. Innovative Risikobewertungsverfahren als Instrumente nachhaltiger Chemikalienpolitik, In: Chemikalienregulierung und Innovationen zum nachhalti-gen Wirtschaften, eds. by B. Hansjürgens, R. Nordbeck, Springer, ISBN 3-7908-1597-7, 2005
[3] Bridging Effect Assessment of Mixtures to Ecosystem Situations and Regulation (BEAM) – Executive Summary Report, 2004
[2] Prediction and Assessment of the Aquatic Toxicity of Mixtures of Chemicals (PREDICT) – Executive Summary Report, 2000
[1] Grimme LH, Altenburger R, Backhaus T, Bödeker W, Faust M, Scholze M: Vorhersagbarkeit und Beurteilung der aquatischen Toxizität von Stoffgemischen, UFZ-Bericht 25/1998, UFZ-Umweltforschungszentrum Leipzig-Halle GmbH, Leipzig, 1998, ISSN: 0948-9452, 320 pages
PhD-Thesis:
Antibiotics as environmental chemicals – aquatic toxicology and combined effects of selected substances in bioluminescence assays with Vibrio fischeri, 1999, DAV Publishers, ISBN 3-934366-29-5
I am author or co-author of a multitude of poster and oral presentations at international con-ferences, especially at the meetings of the Society of Environmental Toxicology and Chemistry. Please enquire for a full list.
